A new apionine weevil, Coelocephalapion camarae, new species, from Mexico is described and illustrated. The new species closely resembles C. germanum (Sharp) of the C. sordidum species group but combines group characters from the C. decoloratum and C. sordidum species groups. The species is under laboratory culture as a potential biocontrol agent for Lantana camara L. (Verbenaceae) in South Africa.